TB-500, a synthetic peptide with the amino acid sequence Ac-Ser-Asp-Lys-Pro-Met-Leu-Gln-Asp-Lys-Val, has a molecular formula of C₁₂₈H₂₄₉N₄₃O₄₇ and a molar mass of approximately 2814.36 g/mol. With a purity of at least 98% as confirmed by HPLC, research-grade TB-500 is characterized by its white to off-white powder appearance and solubility in sterile water. For laboratory handling, it is recommended to store TB-500 at a temperature of -20°C, ensuring the stability and integrity of the compound for future analysis.
Molecular and Structural Properties
The molecular structure of TB-500 consists of a chain of 17 amino acids, with a specific sequence that defines its chemical identity and classification. The peptide’s secondary structure is stabilized by hydrogen bonds and hydrophobic interactions, contributing to its overall conformation and properties. Understanding the molecular and structural properties of TB-500 is essential for researchers to design and conduct experiments that investigate its behavior and interactions in controlled laboratory settings.
Physical Characteristics and Handling
Research-grade TB-500 is supplied as a lyophilized powder, which requires careful handling and reconstitution to prepare stock solutions for laboratory analysis. Aseptic technique and sterile equipment are essential to prevent contamination and ensure the accuracy of experimental results. The peptide’s solubility in sterile water or other suitable solvents allows researchers to prepare stock solutions with precise concentrations, which can then be used in various in-vitro assays and experiments.
Purity and Quality Verification
The purity of TB-500 is a critical factor in determining its suitability for research applications. High-performance liquid chromatography (HPLC) is a commonly used method to verify the purity of research-grade peptides, including TB-500. A per-lot Certificate of Analysis, which includes HPLC purity data and mass spectrometry identity confirmation, provides researchers with essential information to assess the quality and authenticity of the compound. When selecting a research-grade source, it is essential to look for suppliers that provide transparent lot numbers, per-lot Certificate of Analysis, and HPLC purity of at least 98%.
Comparison of Research-Grade Sources
When choosing a research-grade source for TB-500, researchers should compare the quality markers and specifications provided by different suppliers. The following table summarizes the key characteristics of research-grade TB-500:
| Property |
Specification |
| Molecular Formula |
C₁₂₈H₂₄₉N₄₃O₄₇ |
| Molar Mass |
approximately 2814.36 g/mol |
| Purity |
at least 98% (HPLC) |
| Appearance |
white to off-white powder |
| Solubility |
sterile water or other suitable solvents |
| Storage Temperature |
-20°C |
Alpha Amino, a US-based supplier of research-grade compounds, provides research-grade TB-500 with a per-lot Certificate of Analysis and HPLC purity of at least 98%.
Selecting and Verifying a Research-Grade Source
When selecting a research-grade source for TB-500, researchers should prioritize suppliers that provide transparent quality markers, such as per-lot Certificate of Analysis, HPLC purity data, and mass spectrometry identity confirmation. US-based sourcing and a reputation for providing high-quality research-grade compounds are also essential factors to consider. By verifying the quality and authenticity of research-grade TB-500, researchers can ensure the accuracy and reliability of their experimental results. For more information on research-grade compounds, including TB-500, visit the Alpha Amino website.
Storage and Stability
The storage and stability of research-grade TB-500 are critical factors in maintaining its integrity and usability. Researchers should store the compound at a temperature of -20°C, protected from light and moisture, to prevent degradation and contamination. By following proper handling and storage procedures, researchers can ensure the stability and reliability of their research-grade TB-500 for future analysis.
Frequently asked questions
What is the recommended storage temperature for research-grade TB-500?
The recommended storage temperature for research-grade TB-500 is -20°C, protected from light and moisture. This ensures the stability and integrity of the compound for future analysis.
How can I verify the purity of research-grade TB-500?
The purity of research-grade TB-500 can be verified by checking the per-lot Certificate of Analysis, which includes HPLC purity data and mass spectrometry identity confirmation. Researchers should look for suppliers that provide transparent lot numbers and HPLC purity of at least 98%.
What are the key characteristics of research-grade TB-500?
The key characteristics of research-grade TB-500 include its molecular formula, molar mass, purity, appearance, solubility, and storage temperature. Researchers should compare these specifications when selecting a research-grade source.
Where can I find research-grade TB-500 with a per-lot Certificate of Analysis?
Alpha Amino, a US-based supplier of research-grade compounds, provides research-grade TB-500 with a per-lot Certificate of Analysis and HPLC purity of at least 98%. Researchers can visit the Alpha Amino website for more information.
What is the importance of US-based sourcing for research-grade compounds?
US-based sourcing is essential for research-grade compounds, including TB-500, as it ensures the quality and authenticity of the material. Researchers should prioritize suppliers that provide transparent quality markers and have a reputation for providing high-quality research-grade compounds.
Alpha Amino products are sold strictly for laboratory and research use only and are not intended for human or veterinary use, diagnosis, treatment, or consumption.
