GHK-Cu, a tripeptide with the amino acid sequence Gly-His-Lys, has a molecular formula of C₁₄H₂₄N₆O₄Cu and a molar mass of approximately 340.8 g/mol. Research-grade GHK-Cu is typically provided with a purity of ≥98% as confirmed by HPLC and mass spectrometry. For laboratory storage, it is recommended to keep GHK-Cu at a temperature of -20°C, protected from light and moisture, to maintain its stability and potency. When handled as an in-vitro laboratory reference compound, GHK-Cu can be utilized to prepare stock solutions for various research applications, and its quality can be verified through a per-lot Certificate of Analysis, which is essential for ensuring the reliability of research results.
Chemical Identity and Classification
GHK-Cu is classified as a copper-containing tripeptide, consisting of glycine, histidine, and lysine amino acids. Its chemical structure and composition make it a valuable reference compound for various in-vitro studies. The presence of copper in the molecule is significant, as it plays a crucial role in the compound’s chemical properties and potential interactions. As a research-grade material, GHK-Cu is often used as a reference standard for analytical and biochemical assays.
Molecular and Structural Properties
The molecular formula of GHK-Cu, C₁₄H₂₄N₆O₄Cu, indicates the presence of copper, which is coordinated to the histidine and lysine residues. The molar mass of approximately 340.8 g/mol is an important characteristic for calculating the concentration of stock solutions. The amino acid sequence length of three residues contributes to the compound’s overall structure and properties. Understanding the molecular and structural properties of GHK-Cu is essential for its application in laboratory research.
Physical Characteristics and Purity
Research-grade GHK-Cu is typically provided as a white or off-white powder, with a purity of ≥98% as confirmed by HPLC and mass spectrometry. The high purity of the compound is crucial for ensuring the accuracy and reliability of research results. The appearance and purity of GHK-Cu can be verified through a per-lot Certificate of Analysis, which provides detailed information on the compound’s physical and chemical characteristics. When selecting a research-grade source, it is essential to confirm the purity and quality of the material to ensure the validity of research findings.
Purity and Quality Verification
The purity and quality of GHK-Cu can be verified through various analytical techniques, including HPLC and mass spectrometry. A per-lot Certificate of Analysis is essential for confirming the purity, identity, and potency of the compound. Research-grade GHK-Cu should be provided with a Certificate of Analysis that includes detailed information on the compound’s physical and chemical characteristics, such as purity, molar mass, and amino acid sequence. By verifying the purity and quality of GHK-Cu, researchers can ensure the accuracy and reliability of their research results.
Selecting and Verifying a Research-Grade Source
When selecting a research-grade source of GHK-Cu, it is essential to confirm the quality and purity of the material. A reputable supplier, such as Alpha Amino, provides research-grade compounds with a per-lot Certificate of Analysis, ensuring the highest level of quality and purity. Researchers should look for suppliers that provide transparent lot numbers, HPLC purity (commonly ≥98% for research-grade material), and mass-spectrometry identity confirmation. By verifying the quality and purity of GHK-Cu, researchers can ensure the validity of their research findings. For research-grade GHK-Cu, visit the Alpha Amino website to explore their selection of laboratory reference compounds.
Storage and Stability for Laboratory Handling
For laboratory storage, GHK-Cu should be kept at a temperature of -20°C, protected from light and moisture, to maintain its stability and potency. The compound should be handled using aseptic laboratory technique, and sterile transfer and pipetting procedures should be followed to prevent contamination. By following proper storage and handling procedures, researchers can ensure the stability and potency of GHK-Cu for their research applications.
Frequently asked questions
What is the recommended storage temperature for GHK-Cu?
The recommended storage temperature for GHK-Cu is -20°C, protected from light and moisture, to maintain its stability and potency. This temperature range helps to prevent degradation and ensures the compound’s chemical properties remain intact.
How can I verify the purity and quality of GHK-Cu?
The purity and quality of GHK-Cu can be verified through a per-lot Certificate of Analysis, which provides detailed information on the compound’s physical and chemical characteristics, such as purity, molar mass, and amino acid sequence. Researchers should also look for suppliers that provide transparent lot numbers, HPLC purity, and mass-spectrometry identity confirmation.
What is the importance of a per-lot Certificate of Analysis for GHK-Cu?
A per-lot Certificate of Analysis is essential for confirming the purity, identity, and potency of GHK-Cu. It provides detailed information on the compound’s physical and chemical characteristics, ensuring the accuracy and reliability of research results. Researchers should always verify the Certificate of Analysis before purchasing GHK-Cu for their research applications.
How can I prepare in-vitro stock solutions of GHK-Cu for research?
In-vitro stock solutions of GHK-Cu can be prepared by dissolving the compound in a suitable solvent, such as sterile water or a buffer solution, using aseptic laboratory technique and sterile transfer and pipetting procedures. The concentration of the stock solution can be calculated based on the compound’s molar mass and purity, as confirmed by the Certificate of Analysis.
Where can I find research-grade GHK-Cu for my laboratory research?
Research-grade GHK-Cu can be found at reputable suppliers, such as Alpha Amino, which provides high-quality laboratory reference compounds with a per-lot Certificate of Analysis. By selecting a reputable supplier, researchers can ensure the accuracy and reliability of their research results.
Alpha Amino products are sold strictly for laboratory and research use only and are not intended for human or veterinary use, diagnosis, treatment, or consumption.
